by Borja Ibarra | Jun 26, 2018
Viral transcription Influenza A virus is a global public health threat. It is responsible for seasonal epidemics and occasional pandemics of respiratory disease showing substantial morbidity and mortality in humans and a considerable financial burden worldwide....
by Borja Ibarra | Apr 14, 2018
Membrane nanomechanics The dynamin family of proteins contains unique GTPases involved in membrane fission and fusion events throughout the cell. Dynamin is necessary for internalizing essential nutrients, is tightly coupled to cell signaling events, and has been...
by Borja Ibarra | Jun 30, 2017
Synthetic molecular switches Molecular shuttles are perhaps one of the simplest examples of molecular devices and have long been considered candidates for the construction of molecular motors. Structurally, molecular shuttles are [2]rotaxanes in which the macrocycle...
by Borja Ibarra | Jun 30, 2017
Mitochondrial DNA replication dynamics Mitochondria are the energy-producing organelle in animals, and mitochondrial function impacts nearly every aspect of cellular function, being critical for life. A full understanding of the mitochondrial function is in need of...
by Borja Ibarra | Jun 30, 2017
Replicative DNA polymerases Replicative polymerases are key enzymes for genome duplication. Using one strand of the DNA as a template they work as efficient molecular motors, catalyzing the incorporation of the corresponding complementary nucleotide in each position....